This page keeps track of new/upcoming treatment options for Alzheimer’s disease (AD). What’s in development? What’s promising? What’s available soon? Find out below… Current topics include BPN14770, kynurenines, gene therapy, and more.
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News
- Alzheimer’s may be treated with diabetes drugs Nov 5, 2018
- New Alzheimer’s drug draws on 40 years of research Oct 8, 2018
- Could repurposing a liver disease drug improve mitochondrial dysfunction in Alzheimer’s? Sep 3, 2018
- Research reveals a potential new biotherapy for Alzheimer’s disease Aug 29, 2018
- Experimental Alzheimer’s drug stirs hope after early trials Jul 26, 2018
- New Alzheimer’s Drug Slows Memory Loss in Early Trial Results Jul 25, 2018
- Hopes rise again for a drug to slow Alzheimer’s disease Jul 25, 2018
Research
- Targeting GSK3 signaling as a potential therapy of neurodegenerative diseases and aging Sep 26, 2018
- 5-HT3 receptor antagonist ondansetron may help reduce cognitive deficits in Alzheimer’s disease Sep 19, 2018
- Time course of focused ultrasound effects on β-amyloid plaque pathology in the TgCRND8 mouse model of Alzheimer’s disease Sep 18, 2018
- Rollercoaster ride of kynurenines: Steering the wheel towards neuroprotection in Alzheimer’s disease Sep 18, 2018
- The BACE-1 inhibitor CNP520 for prevention trials in Alzheimer’s disease Sep 17, 2018
- The Protective Effect of Betulinic Acid on Microvascular Responsivity and Protein Expression in Alzheimer Disease Induced by Cerebral Micro‐Injection of Beta‐Amyloid and Streptozotocin Sep 4, 2018
- Microdose Lithium NP03 Diminishes Pre-Plaque Oxidative Damage and Neuroinflammation in a Rat Model of Alzheimer’s-like Amyloidosis Sep 4, 2018
- Ellagic acid: Insights into its neuroprotective and cognitive enhancement effects in sporadic Alzheimer’s disease Aug 30, 2018
- Natural Scaffolds with Multi-Target Activity for the Potential Treatment of Alzheimer’s Disease Aug 29, 2018
- TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer’s disease Aug 29, 2018
- Ursodeoxycholic Acid Improves Mitochondrial Function and Redistributes Drp1 in Fibroblasts from Patients with either Sporadic or Familial Alzheimer’s Disease Aug 29, 2018
- Current progress on peroxisome proliferator-activated receptor gamma agonist as an emerging therapeutic approach for the treatment of Alzheimer’s disease: An update Aug 27, 2018
- Aroylhydrazones constitute a promising class of ‘metal-protein attenuating compounds’ for the treatment of Alzheimer’s disease: a proof-of-concept based on the study of the interactions between zinc(II) and pyridine-2-carboxaldehyde isonicotinoyl hydrazone Aug 25, 2018
- Novel multi-target compounds in the quest for new chemotherapies against Alzheimer’s disease: An experimental and theoretical study Aug 25, 2018
- Neuroprotective effects of salidroside administration in a mouse model of Alzheimer’s disease May 17, 2018
- Young Blood Plasma Administration to Fight Alzheimer’s Disease? Apr 1, 2018
- Spatial memory recovery in Alzheimer’s rat model by electromagnetic field exposure Dec 17, 2017
- Chalcone-based carbamates for Alzheimer’s disease treatment May 12, 2017
Clinical Trials
- REGEnLIFE RGn530 – Feasibility Pilot Oct 16, 2018
- Efficacy and Safety of 26-Week Treatment of AR1001 in Patients With Mild to Moderate Alzheimer’s Disease Sep 4, 2018
- Gene Therapy for APOE4 Homozygote of Alzheimer’s Disease Aug 29, 2018
- A Phase I Study for Safety and Tolerability of AL002 Aug 22, 2018
- A Multiple Ascending Dose Study of COR388 Jul 17, 2018
- Study to Evaluate the Effect of CT1812 Treatment on Amyloid Beta Oligomer Displacement Into CSF in Subjects With Mild to Moderate Alzheimer’s Disease Jun 6, 2018
- A Study to Investigate Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-63733657 in Healthy Subjects and Subjects With Alzheimer’s Disease May 31, 2018
- Effect of CT1812 Treatment on Brain Synaptic Density May 28, 2018